Thermo Fisher Scientific RPGR Polyclonal Antibody
RPGR 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. Human, Mouse, Rat 반응성. 고순도 (>95%) 항원 친화 크로마토그래피 정제. 장기 보관 시 -20°C에서 안정적.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from Human RPGR, corresponding to amino acid residues L986–N1009 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2554061 |
Product Specific Information
This antibody detects endogenous RPGR protein at molecular weights of 70, 83, 90, 113, and 127 kDa.
Purity is >95% by SDS-PAGE.
Target Information
The RPGR gene encodes a protein containing six RCC1-like domains (RLDs), characteristic of guanine nucleotide exchange factors.
The protein localizes to the Golgi body and interacts with RPGRIP1. It is essential for rod photoreceptor viability and mutations are associated with X-linked retinitis pigmentosa (XLRP).
Multiple alternatively spliced transcript variants exist, encoding different isoforms, with only some full-length forms determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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