Thermo Fisher Scientific BCL7A Polyclonal Antibody
BCL7A 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot, ICC/IF, Flow cytometry 등 다양한 응용 가능. 인간에 반응하며, 다른 종에서도 예측 반응. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 10 µg/mL | - |
| Flow Cytometry (Flow) | 10 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (MKLEASQQNSEEM) corresponding to the C-terminus amino acids of BCL7A (aa 198–210) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977865 |
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
The BCL7A gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. This translocation disrupts the N-terminal region of the gene product, which may contribute to the pathogenesis of certain high-grade B cell non-Hodgkin lymphomas.
The N-terminal segment involved shares strong sequence similarity with BCL7B and BCL7C.
Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-17933_BCL7A_Q4VC05-1_Goat.svg, PA5-17933_BCL7A_Q4VC05-1_Goat_PDP.jpeg)
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