Thermo Fisher Scientific Tankyrase Polyclonal Antibody
Tankyrase 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot에 적합합니다. 인간 종에 반응하며 Wnt 신호전달 및 텔로미어 조절 연구에 활용됩니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
- 판매단위
- pk
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Thermo Fisher Scientific Tankyrase Polyclonal Antibody
Applications
- Western Blot (WB): 0.5–1.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (recombinant) corresponding to the N-terminus amino acids of TNKS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11001304 |
Target Information
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length regulation, and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, key components of the beta-catenin destruction complex. Mediates PARsylation of BLZF1, CASC3, and TERF1, contributing to telomere length regulation and centrosome maturation. May also play roles in vesicle trafficking and spindle pole assembly, and stimulates 26S proteasome activity. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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