Thermo Fisher Scientific SOCS3 Polyclonal Antibody
SOCS3 단백질의 C-말단 서열을 인식하는 염소 유래 폴리클로날 항체입니다. Western blot에 최적화되어 있으며 다양한 종에서 반응이 예측됩니다. 액상 형태로 제공되며 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA517934
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (PIREFLDQYDAPL) corresponding to the C-terminus amino acids of SOCS3 (aa 213–225) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11009496 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
Cytokine receptor signaling is negatively regulated by the SOCS (Suppressor of Cytokine Signaling) family, which includes eight members: SOCS1–7 and CIS. These proteins contain an N-terminal region, a central SH2 domain, and a C-terminal SOCS box motif. SOCS proteins function as part of a negative feedback loop that modulates cytokine signal transduction via STAT-induced transcriptional mechanisms. Expression of SOCS genes is rapidly induced by cytokines, and each member can inhibit signaling through distinct mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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