Thermo Fisher Scientific NBN Monoclonal Antibody (OTI3A2), TrueMAB
NBN 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot 및 IHC(P) 검증 완료. Human 시료 반응성. Lyophilized 형태로 공급되며 재구성 후 1 mg/mL 농도. PBS buffer(8% trehalose) 함유, -20°C 보관.
- 카탈로그번호
- CF801218
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 461–754 of human NBN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The p95 gene (identical to NBS1 and nibrin) is a component of the hMre11/hRad50 double-strand break complex. This complex is implicated in Nijmegen breakage syndrome, an autosomal recessive disorder characterized by increased cancer incidence, cell cycle checkpoint defects, and sensitivity to ionizing radiation. This highlights a molecular link between double-strand break repair and cell cycle checkpoint control.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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