Thermo Fisher Scientific NBN Monoclonal Antibody (OTI5A6), TrueMAB
인간 NBN 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. 동결건조 형태로 제공되며, PBS 완충액과 트레할로스를 포함합니다. 연구용으로만 사용 가능하며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 461–754 of human NBN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, avoid freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.
Target Information
The p95 gene (NBS1/nibrin) is part of the hMre11/hRad50 double-strand break complex, which plays a critical role in DNA double-strand break repair. Mutations in this gene are associated with Nijmegen breakage syndrome, characterized by increased cancer susceptibility, cell cycle checkpoint defects, and radiation sensitivity. This highlights the molecular link between DNA repair and cell cycle regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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