Thermo Fisher Scientific NBN Monoclonal Antibody (OTI1G10), TrueMAB
NBN 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, 동결건조 형태로 제공. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- CF801217
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G10 |
| Immunogen | Human recombinant protein fragment (aa 461–754 of human NBN produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of ~1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The p95 gene (also known as NBS1 or nibrin) is a component of the hMre11/hRad50 double-strand break repair complex.
Mutations in this gene are associated with Nijmegen breakage syndrome, characterized by increased cancer risk, cell cycle checkpoint defects, and sensitivity to ionizing radiation.
This reveals a direct molecular link between double-strand break repair and cell cycle checkpoint control.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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