Thermo Fisher Scientific ATF1 Polyclonal Antibody
Human ATF1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Rabbit IgG 호스트 기반입니다. IHC(P)에서 1:500–1:2000 희석으로 사용 가능하며, 보존제가 없는 액상 형태로 제공됩니다. 연구용으로 세포 성장 및 신호전달 관련 단백질 분석에 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of Human ATF1/Protein TREB36 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787682 |
Product Specific Information
- This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human ATF1/Protein TREB36.
Target Information
The ATF1 gene encodes an activating transcription factor belonging to the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates downstream target genes involved in cellular growth, survival, and other physiological processes.
ATF1 is phosphorylated at serine 63 by various kinases, enhancing its transactivation and transcriptional activities and promoting cell transformation.
Fusion of ATF1 with FUS (chromosome 16) or EWSR1 (chromosome 22) generates chimeric proteins found in angiomatoid fibrous histiocytoma and clear cell sarcoma.
A pseudogene is located on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-80357_ATF1_P18846-1_Rabbit.svg, PA5-80357_ATF1_P18846-1_Rabbit_PDP.jpeg)
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