Thermo Fisher Scientific ART3 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:2,500–1:10,000

ELISA

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

• Preservative-free formulation.
• To prevent contamination, add sodium azide (final concentration 0.05%–0.1%).
• Specificity: Human ART3.

Target Information

Mono-ADP-ribosylation transfers the ADP-ribose moiety from NAD⁺ to a specific amino acid in the target protein.
Rodent mono-ADP-ribosyltransferase RT6 is a GPI-anchored membrane protein expressed on T lymphocytes in rats and mice.
Human ART3 protein (367 amino acids, ~41.5 kDa) includes:

• Hydrophobic peptide signal at N terminus
• Three consensus motifs for ADP-ribose transfer enzymes
• Hydrophobic C-terminal sequence (GPI-anchored protein characteristic)
• Novel motif repeated three times at C terminus
• One potential glycosylation site

ART3 and rodent RT6 share 35% amino acid identity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.