Thermo Fisher Scientific PTP1B Polyclonal Antibody
PTP1B 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성을 가지며, Protein A로 정제된 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human PTP-1B (amino acids 1–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PTP1B (PTPN1) is a tyrosine-protein phosphatase that regulates the endoplasmic reticulum unfolded protein response by mediating dephosphorylation of EIF2AK3/PERK, thereby inactivating its kinase activity. It also participates in CKII- and p60c-src-induced signal transduction cascades, regulates the EFNA5-EPHA3 signaling pathway affecting cell organization and repulsion, and modulates hepatocyte growth factor receptor (MET) signaling through dephosphorylation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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