Thermo Fisher Scientific Nurr1 Polyclonal Antibody
Nurr1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫트 반응성. WB, IHC, ICC, ELISA 등 다양한 응용 가능. Protein A 정제, 액상 형태, -20°C 보관.
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- BS-0178R
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- pk
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Thermo Fisher Scientific Nurr1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–400 |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Nurr1 (UniProt ID: P43354-1, Antigen Range: 301–400) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Nuclear receptor related 1 protein (Nurr1), also known as NR4A2 (nuclear receptor subfamily 4, group A, member 2), is encoded by the NR4A2 gene in humans. NURR1 is a member of the nuclear receptor family of intracellular transcription factors and plays a key role in maintaining the dopaminergic system of the brain. Mutations in this gene have been associated with dopaminergic dysfunction disorders such as Parkinson’s disease, schizophrenia, and manic depression. Misregulation may also be linked to rheumatoid arthritis. Four transcript variants encoding distinct isoforms have been identified, with additional splice variants potentially existing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: BS-0178R_Nurr1_P43354-1_Rabbit.svg, BS-0178R_Nurr1_P43354-1_Rabbit_PDP.jpeg)
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