Thermo Fisher Scientific Cytokeratin 6 (KRT6) (Hyperproliferation-Related Keratin) Monoclonal Antibody (LHK6 (LHK6B))

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

0.1-0.2 µg/mL

-

Immunocytochemistry (ICC/IF)

1-2 µg/mL

-

Flow Cytometry (Flow)

0.5-1 µg/10^6 cells

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

LHK6 (LHK6B)

Immunogen

A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from C-terminus of human keratin 6 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytokeratin 6,uniProtId:P02538-1,ncbiNodeId:9606,antigenRange:553-564,antigenLength:564,antigenImageFileName:3853-MSM1-P1ABX_Cytokeratin_6_P02538-1_House_mouse.svg,antigenImageFileNamePDP:3853-MSM1-P1ABX_Cytokeratin_6_P02538-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:Cytokeratin 6,uniProtId:P48668-1,ncbiNodeId:9606,antigenRange:553-564,antigenLength:564,antigenImageFileName:3853-MSM1-P1ABX_Cytokeratin_6_P48668-1_House_mouse.svg,antigenImageFileNamePDP:3853-MSM1-P1ABX_Cytokeratin_6_P48668-1_House_mouse_PDP.jpeg,sortOrder:2},{targetFamily:Cytokeratin 6,uniProtId:P04259-1,ncbiNodeId:9606,antigenRange:553-564,antigenLength:564,antigenImageFileName:3853-MSM1-P1ABX_Cytokeratin_6_P04259-1_House_mouse.svg,antigenImageFileNamePDP:3853-MSM1-P1ABX_Cytokeratin_6_P04259-1_House_mouse_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.