Thermo Fisher Scientific Cytokeratin 6 (KRT6) (Hyperproliferation-Related Keratin) Monoclonal Antibody (LHK6 (LHK6B))
Cytokeratin 6(KRT6) 단백질을 인식하는 Mouse monoclonal antibody로, 인간 및 생쥐 시료에 반응합니다. IHC, ICC, Flow Cytometry 등 다양한 응용 가능하며, Protein A/G로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.1–0.2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LHK6 (LHK6B) |
| Immunogen | Synthetic peptide of 11 amino acids (GSSTIKYTTTS) from C-terminus of human keratin 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, also referred to as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles, suprabasal cells of various internal stratified epithelia, and in epidermis under both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas and is associated with cellular differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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