Thermo Fisher Scientific Cytokeratin 6/KRT6 (Pan; a,b,c) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (rKRT6/9402)
Basal cell 마커로 사용되는 Cytokeratin 6/KRT6 단백질을 인식하는 재조합 토끼 단일클론 항체. 인체 반응성, IHC(P) 적용 가능, 높은 특이성과 재현성을 제공. 단백질 A/G 정제, 4°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rKRT6/9402 |
| Immunogen | Recombinant fragment (around aa400–564) of human KRT6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Human tonsil or basal cell carcinoma (BCC)
- Cellular Location: Cytoplasm
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, also known as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles, suprabasal cells of various internal stratified epithelia, and epidermis under both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas and is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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