Thermo Fisher Scientific Cytokeratin 6 (Basal Cell Marker) Monoclonal Antibody (SPM269)
Cytokeratin 6 단백질을 표지하는 단클론 항체로, 인간 및 생쥐 시료에서 기저세포 마커로 사용됩니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합하며, 고순도 Protein A/G 정제 및 PBS 용액 형태로 제공됩니다.
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Thermo Fisher Scientific Cytokeratin 6 (Basal Cell Marker) Monoclonal Antibody (SPM269)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM269 |
| Immunogen | A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from C-terminus of human keratin 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region and are known as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles, suprabasal cells of internal stratified epithelia, and epidermis under normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas and is associated with cellular differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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