Thermo Fisher Scientific Cytokeratin 6 (Basal Cell Marker) Monoclonal Antibody (SPM269)
Cytokeratin 6 단백질을 인식하는 단일클론 항체로, 기저세포 마커로 사용됩니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합하며, Human 및 Mouse 시료에 반응합니다. Protein A/G 정제, 액상 형태로 제공되며 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM269 |
| Immunogen | A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from the C-terminus of human keratin 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, also known as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles, suprabasal cells of various internal stratified epithelia, and in the epidermis under both normal and hyperproliferative conditions.
Epidermal injury induces keratinocytes to express CK6 and CK16.
CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas and is particularly associated with differentiation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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