Thermo Fisher Scientific Ku70 Polyclonal Antibody
Ku70 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF, ELISA에 적합. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 액상 형태. PBS/glycerol buffer에 보존되며 -20°C에서 보관.
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Thermo Fisher Scientific Ku70 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:3,000–1:18,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 408–609 of human Ku70 (NP_0014601) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913628 |
Product Specific Information
Positive test controls include SKOV3, COS7, SW480, HeLa, Mouse brain, Mouse liver, Mouse skeletal muscle, and Rat liver.
The target is usually found in the following locations: Chromosome, Nucleus.
Immunogen sequence:
PYFVALVPQE EELDDQKIQV TPPGFQLVFL PFADDKRKMP FTEKIMATPE QVGKMKAIVE KLRFTYRSDS FENPVLQQHF RNLEALALDL MEPEQAVDLT LPKVEAMNKR LGSLVDEFKE LVYPPDYNPE GKVTKRKHDN EGSGSKRPKV EYSEEELKTH ISKGTLGKFT VPMLKEACRA YGLKSGLKKQ ELLEALTKHF QD
Target Information
XRCC6 is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa.
The complex functions as a single-stranded DNA-dependent ATP-dependent helicase.
It may be involved in the repair of nonhomologous DNA ends such as those required for double-strand break repair, transposition, and V(D)J recombination.
High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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