Thermo Fisher Scientific IKK gamma Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 250-390 of human IKK gamma (NP_0036301) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IKK gamma,uniProtId:Q9Y6K9-1,ncbiNodeId:9606,antigenRange:250-390,antigenLength:419,antigenImageFileName:PA5-120057_IKK_gamma_Q9Y6K9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120057_IKK_gamma_Q9Y6K9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.58 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913629

Product Specific Information

Positive test controls include: HeLa, Jurkat, Mouse brain, Rat brain. The target is usually found in the following locations: Cytoplasm, Nucleus.

Immunogen sequence: VGSERKRGMQ LEDLKQQLQQ AEEALVAKQE VIDKLKEEAE QHKIVMETVP VLKAQADIYK ADFQAERQAR EKLAEKKELL QEQLEQLQRE YSKLKASCQE SARIEDMRKR HVEVSQAPLP PAPAYLSSPL ALPSQRRSPP E

Target Information

IKK gamma is the regulatory subunit of the inhibitor of the kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.