Thermo Fisher Scientific KIR2DL4 Polyclonal Antibody
KIR2DL4 단백질을 인식하는 Rabbit Polyclonal 항체로 Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 사용 가능하며, 고순도의 Affinity Chromatography 정제 제품입니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 22–242 of human KIR2DL4 (NP_0022465) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805135 |
Product Specific Information
Immunogen sequence:
WAHVGGQDKP FCSAWPSAVV PQGGHVTLRC HYRRGFNIFT LYKKDGVPVP ELYNRIFWNS FLISPVTPAH AGTYRCRGFH PHSPTEWSAP SNPLVIMVTG LYEKPSLTAR PGPTVRAGEN VTLSCSSQSS FDIYHLSREG EAHELRLPAV PSINGTFQAD FPLGPATHGE TYRCFGSFHG SPYEWSDPSD PLPVSVTGNP SSSWPSPTEP SFKTGIARHL H
Positive Samples: HeLa, SKOV3, PC-12, Mouse uterus, Mouse kidney
Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
CD158d / KIR2DL4 is a member of the KIR family that shares structural features with both activating and inhibitory receptors. It contains a cytoplasmic ITIM domain, suggesting inhibitory function, and a transmembrane domain similar to activating KIRs. CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but ligation with soluble antibodies can induce IFN-gamma secretion. It binds both membrane-bound and soluble forms of its ligand HLA-G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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