Thermo Fisher Scientific TP53I11 Polyclonal Antibody
TP53I11 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ELISA에 적합하며, 고순도의 액상 형태로 제공됩니다. 세포막 단백질 검출 및 종양 억제 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–70 of human TP53I11 (NP_001245249.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.69 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805145 |
Product Specific Information
- Immunogen sequence: MAAKQPPPLM KKHSQTDLVS RLKTRKILGV GGEDDDGEVH RSKISQVLGN EIKFTIREPL GLRVWQFVSA
- Positive Samples: HeLa, Mouse brain
- Cellular Location: Membrane, Multi-pass membrane protein
Target Information
TP53I11 is a 177 amino acid tumor suppressor protein belonging to the p53-induced protein (PIG) family. The PIG gene family encodes redox-controlling proteins involved in p53 tumor suppressor activity. PIG11 may participate in arsenic trioxide (As₂O₃)-induced apoptosis and play a role in tumor suppression by promoting cell apoptosis. The gene encoding PIG11 is located on human chromosome 11, which contains over 1,400 genes and represents approximately 4% of the human genome.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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