Thermo Fisher Scientific TLX1 Polyclonal Antibody
TLX1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 적합하며, 고순도의 Affinity Chromatography 정제 항체입니다. 핵 내 전사인자 TLX1 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 1–190 of human TLX1 (NP_0011824461) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.46 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805149 |
Product Specific Information
Immunogen sequence:
MEHLGPHHLH PGHAEPISFG IDQILNSPDQ GGCMGPASRL QDGEYGLGCL VGGAYTYGGG GSAAATGAGG AGAYGTGGPG GPGGPAGGGG ACSMGPLTGS YNVNMALAGG PGPGGGGGSS GGAGALSAAG VIRVPAHRPL AGAVAHPQPL ATGLPTVPSV PAMPGVNNLT GLTFPWMESN RRYTKDRFTG
Positive Samples: Jurkat, K562, Mouse spleen, Rat spleen
Cellular Location: Nucleus
Target Information
The Hox proteins play a role in embryonic development and cellular differentiation by regulating downstream target genes.
TLX1 (also known as HOX11) is a DNA-binding nuclear transcription factor located outside the four mammalian Hox clusters.
It encodes a homeobox-domain-containing protein with a glycine- and proline-rich N-terminus.
TLX1 is essential for spleen development and cell survival, and is highly expressed in T-cell leukemia and lymphoid neoplasias due to translocation.
TLX1-deficient mice lack a spleen.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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