
Thermo Fisher Scientific HEXA Polyclonal Antibody
HEXA 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 인간 시료에 반응. 동결건조 형태로 제공되며 재구성 시 500 µg/mL 농도. 항원 친화 크로마토그래피로 정제됨.
- 카탈로그번호
- PA579358
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human HEXA (513–529aa, QAQPLNVGFCEQEFEQT) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746474 |
Product Specific Information
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines.
Beta-hexosaminidase is composed of two subunits, alpha and beta, encoded by separate genes. Both subunits belong to family 20 of glycosyl hydrolases.
Mutations in either subunit gene cause accumulation of GM2 ganglioside in neurons, leading to neurodegenerative disorders known as GM2 gangliosidoses. Mutations in the alpha subunit gene cause Tay-Sachs disease (GM2-gangliosidosis type I).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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