Thermo Fisher Scientific HEXA Polyclonal Antibody

Applications

• Western Blot (WB): 0.1–0.5 µg/mL

Product Specifications

Product Specific Information

• Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2 and other molecules containing terminal N-acetyl hexosamines.
Beta-hexosaminidase is composed of two subunits, alpha and beta, encoded by separate genes. Both subunits belong to family 20 of glycosyl hydrolases.
Mutations in either subunit gene cause accumulation of GM2 ganglioside in neurons, leading to neurodegenerative disorders known as GM2 gangliosidoses. Mutations in the alpha subunit gene cause Tay-Sachs disease (GM2-gangliosidosis type I).

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.