Thermo Fisher Scientific CD204 Polyclonal Antibody
CD204 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 적합. 인간 및 마우스 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용에 최적화.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD204 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | View 1 publication |
| Flow Cytometry (Flow) | 2–5 µg/million cells | - |
| in situ PLA (PLA) | Assay-Dependent | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide made to an internal portion of the human protein (within residues 400–450). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.00 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 30% glycerol |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154270 |
Product Specific Information
Suggested positive control: antigen standard for MSR1 (transient overexpression lysate), human liver protein.
Target Information
CD204 gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors are macrophage-specific trimeric integral membrane glycoproteins involved in macrophage-associated physiological and pathological processes such as atherosclerosis, Alzheimer’s disease, and host defense.
- Isoforms type 1 and 2 mediate endocytosis of modified low-density lipoproteins (LDLs).
- Isoform type 3 does not internalize modified LDL and is trapped within the endoplasmic reticulum.
- Isoform type 3 can inhibit the function of isoforms type 1 and 2, suggesting a regulatory mechanism for scavenger receptor activity in macrophages.
- Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.