Thermo Fisher Scientific RAB7 Polyclonal Antibody
RAB7 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB 및 ICC/IF에 사용 가능. 인간 RAB7A full-length recombinant 단백질로부터 제작. 세포 내 소포 수송 및 말단소체-리소좀 경로 연구에 적합. 연구용 전용 제품.
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Thermo Fisher Scientific RAB7 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length human RAB7A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11153999 |
Product Specific Information
Suggested positive control: antigen standard for RAB7A (transient overexpression lysate), HeLa whole cell lysate.
Target Information
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic and endocytic pathways.
This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. It is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori.
Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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