Thermo Fisher Scientific DENND4C Monoclonal Antibody (3E8), FITC
DENND4C 단백질을 표적하는 FITC 결합 단클론 항체로, Western blot, ICC/IF, IP 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 Protein G 정제, 1 mg/mL 농도. 4°C 암저장, 형광 최대치 498/517 nm.
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Thermo Fisher Scientific DENND4C Monoclonal Antibody (3E8), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E8 |
| Immunogen | Full Length Human Recombinant DENND4C protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.1 mM sodium bicarbonate/PBS, pH 7.4, with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932415 |
Additional Formats
Product Specific Information
A 1:1,000 dilution of MA5-45961 was sufficient for detection of DENND4C in A549 and MEF cells by Western blot analysis. Detects approximately 213 kDa.
Target Information
DENND4C is a guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. This process stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicle delivery to the plasma membrane in response to insulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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