Thermo Fisher Scientific PDCD1 Monoclonal Antibody (UMAB222), UltraMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

T-cell activation is regulated by PD-1 (also known as PDCD-1), which mediates inhibitory signals upon binding its ligands PDL-1 and PDL-2.
These interactions help prevent overactivation of immune responses in the absence of danger signals such as LPS.
PD-1 deficiency leads to hyperactivated immune systems and autoimmune conditions.
Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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