Thermo Fisher Scientific TRPC3 Polyclonal Antibody
TRPC3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(F) 실험에 적합합니다. 인간, 마우스, 랫 등 다양한 종에 반응하며, 합성 펩타이드를 면역원으로 사용했습니다. 동결건조 형태로 제공되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:500 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from rat TRPC3 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in mouse and human.
- Specificity: TRPC3.
Target Information
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the canonical TRP (TRPC) family.
The seven members of this family share activation through PLC-coupled receptors and are suggested to be components of receptor-regulated cation channels in various cell types.
Members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, indicating a possible mechanism of activation via PLC-coupled receptors.
TRPC3 encodes a Ca²⁺-permeant channel that is agonist-activated but not store-operated or directly receptor-activated.
TRPC3 interacts with TRPC6 and TRPC7 to form functional tetrameric channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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