Thermo Fisher Scientific TRPV4 Polyclonal Antibody
TRPV4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
- 카탈로그번호
- OST00199W-100UL
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TRPV4 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TRPV4.
Target Information
TRPV4 (Transient Receptor Potential Cation Channel Subfamily V Member 4) is a cation-selective channel activated in response to systemic osmotic pressure. It is a non-selective, calcium-permeant cation channel involved in osmotic sensitivity and mechanosensitivity.
TRPV4 belongs to the OSM9-like transient receptor potential channel (OTRPC) subfamily in the TRP superfamily of ion channels.
Mutations in the TRPV4 gene are associated with spondylometaphyseal and metatropic dysplasia, and hereditary motor and sensory neuropathy type IIC.
Diseases related to TRPV4 include Metatropic Dysplasia and Spondylometaphyseal Dysplasia, Kozlowski Type.
Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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