Thermo Fisher Scientific CD158d Monoclonal Antibody (33), PE-Cyanine7
인간 CD158d/KIR2DL4 인식 단클론 항체로, PE-Cyanine7으로 결합된 형광 표지 제품입니다. NK 세포 표지자 분석용으로 Flow Cytometry에 적합하며, 4°C에서 암소 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA538751
- 판매단위
- pk
카탈로그
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 4 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 33 |
| Immunogen | NK3.3 cells and KIR2DL4-Ig fusion protein |
| Conjugate | PE-Cyanine7 |
| Excitation / Emission Max | 569 / 780 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898663 |
Product Specific Information
This antibody recognizes the extracellular portion of CD158d / KIR2DL4, a 45 kDa NK cell marker. Cell surface expression and function of CD158d / KIR2DL4 depend on the genotype of individual donors.
Target Information
CD158d / KIR2DL4 is a member of the KIR family that shares structural features with both activating and inhibitory receptors. It contains a cytoplasmic ITIM, suggesting an inhibitory function, but also a transmembrane domain similar to activating KIRs. CD158d acts as an inhibitory receptor for peripheral and uterine NK cells; however, ligation with soluble antibodies can induce IFN-gamma secretion. It binds both membrane-bound and soluble forms of its ligand HLA-G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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