Thermo Fisher Scientific CD73 Monoclonal Antibody (AD2), PE-Cyanine5
CD73 단백질을 인식하는 AD2 클론의 마우스 단일클론 항체로, PE-Cyanine5 형광 표지. 인간 및 비인간 영장류 반응성. 유세포 분석(Flow Cytometry)에 적합하며, 4°C 암소 보관. 연구용으로만 사용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 4 µL/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AD2 |
| Immunogen | pre-B leukemia cells |
| Conjugate | PE-Cyanine5 |
| Excitation / Emission Max | 568 / 666 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898664 |
Product Specific Information
This antibody recognizes CD73, a 70 kDa GPI-anchored 5'-nucleotidase expressed predominantly on the surface of T and B cell subsets, follicular dendritic cells, and endothelial cells.
Target Information
CD73 (Ecto-5'-nucleotidase, 5'-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5'-mononucleotides to nucleosides, with AMP as the preferred substrate.
It is a dimer of two identical 70 kDa subunits attached to the plasma membrane via a glycosyl phosphatidylinositol linkage.
CD73 serves as a marker of lymphocyte differentiation, and its deficiency is associated with various immunodeficiency diseases.
Defects in the CD73 gene can lead to calcification of joints and arteries, and intestinal tuberculosis.
Two transcript variants encoding different isoforms of CD73 have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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