Thermo Fisher Scientific CD158d Monoclonal Antibody (mAb#33), PE-Cyanine5
CD158d/KIR2DL4 인식 단클론 항체로, PE-Cyanine5로 표지되어 NK 세포 표면 단백질 분석에 적합. Flow Cytometry에 사용 가능하며, 인간 시료 반응성. 4°C 암소 보관, 동결 금지.
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Applications
- Flow Cytometry (Flow): 4 µL/1x10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | mAb#33 |
| Immunogen | NK3.3 cells and KIR2DL4-Ig fusion protein |
| Conjugate | PE-Cyanine5 |
| Excitation / Emission Max | 568 / 666 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898662 |
Additional Formats
Product Specific Information
This antibody recognizes the extracellular portion of CD158d / KIR2DL4, a 45 kDa NK cell marker.
Cell surface expression and function of CD158d / KIR2DL4 depend on the genotype of individual donors.
Target Information
CD158d / KIR2DL4 is a KIR family member sharing structural features of both activating and inhibitory receptors.
It contains a cytoplasmic ITIM domain (suggesting inhibitory function) and a transmembrane domain similar to activating KIRs.
CD158d acts as an inhibitory receptor for peripheral and uterine NK cells, but ligation with soluble mAbs can induce IFN-gamma secretion.
It binds both membrane-bound and soluble forms of its ligand, HLA-G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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