Thermo Fisher Scientific NKIRAS1 Monoclonal Antibody (OTI1D2), TrueMAB
인간 NKIRAS1 단백질을 인식하는 Mouse IgG1 단클론 항체. Western blot 및 Immunocytochemistry에 적합. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 용이. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D2 |
| Immunogen | Full length human recombinant protein of human NKIRAS1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are small Ras-like GTPases that associate with Ikappa-B, an inhibitor of NF-kappa-B.
Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta, with Ikappa-B-beta containing a unique 47-amino acid region within its ankyrin domain.
Inactive Ikappa-B-alpha–NF-kappa-B complexes shuttle between nucleus and cytoplasm, while Ikappa-B-beta–NF-kappa-B complexes remain in the cytoplasm.
KappaB-ras proteins preferentially bind Ikappa-B-beta through this unique insert, modulating its localization and degradation rate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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