Thermo Fisher Scientific MRPL11 Monoclonal Antibody (OTI1E5), TrueMAB
MRPL11 단백질을 인식하는 Mouse Monoclonal 항체로, Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며, 무보존제 동결건조 형태로 제공. 재구성 시 1 mg/mL 농도로 조제 가능하며, 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E5 |
| Immunogen | Full length human recombinant protein of human MRPL11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within mitochondria.
Mitochondrial ribosomes (mitoribosomes) consist of a small 28S and a large 39S subunit, with about 75% protein to rRNA composition, opposite to that of prokaryotic ribosomes.
Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA.
The MRPL11 gene encodes a protein of the 39S subunit, with three transcript variants producing different isoforms.
Pseudogenes corresponding to MRPL11 are located on chromosomes 5q and 12q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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