Thermo Fisher Scientific Phospho-ETV6 (Ser257) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000

Product Specifications

Target Information

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains:

• N-terminal pointed (PNT) domain: involved in protein-protein interactions with itself and other proteins
• C-terminal DNA-binding domain: responsible for DNA interaction

Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network.
This gene is also known to be involved in numerous chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.