Thermo Fisher Scientific Phospho-ETV6 (Ser257) Polyclonal Antibody
인간 Tel 단백질의 Ser257 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 1:1,000–1:3,000 희석 권장. 액상 형태로 제공되며 -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Tel around the phosphorylation site of Ser257 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817446 |
Target Information
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains:
- N-terminal pointed (PNT) domain: involved in protein-protein interactions with itself and other proteins
- C-terminal DNA-binding domain: responsible for DNA interaction
Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network.
This gene is also known to be involved in numerous chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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