Thermo Fisher Scientific Phospho-PDGFRA/PDGFRB (Tyr849, Tyr857) Monoclonal Antibody (T.564.8)
PDGFRA/PDGFRB 인산화 형태(Tyr849, Tyr857)를 인식하는 토끼 단클론 항체로, Western blot 및 면역침강에 적합합니다. 친화 크로마토그래피로 정제되었으며, Human, Mouse, Rat에 반응합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T.564.8 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr857 of human PDGF receptor β |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 632 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10987513 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors act as mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides.
Studies in knockout mice indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development, as heterozygous mice exhibit defective kidney phenotypes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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