Thermo Fisher Scientific IL2RG Monoclonal Antibody (644346)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

2.5 µg per million cells

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

644346

Immunogen

Sf 21-derived recombinant mouse Common gamma Chain/IL-2 R gamma Trp23-Ala263 (predicted) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL2RG (CD132),uniProtId:P34902-1,ncbiNodeId:10090,antigenRange:23-263,antigenLength:369,antigenImageFileName:MA5-24290_IL2RG_CD132_P34902-1_Rat.svg,antigenImageFileNamePDP:MA5-24290_IL2RG_CD132_P34902-1_Rat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608936

Product Specific Information

In direct ELISAs, no cross-reactivity with recombinant mouse (rm) IL-2 R alpha, rmIL-2 R beta, recombinant human (rh) IL-2 R gamma, rhIL-15 R alpha, recombinant rat IL-2 R alpha, or recombinant canine IL-2 R alpha is observed.

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

Target Information

IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.