Thermo Fisher Scientific IL2RG Monoclonal Antibody (633162)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

2.5 µg per million cells

-

Neutralization (Neu)

0.08-0.4 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

633162

Immunogen

Sf 21-derived recombinant human Common gamma Chain/IL-2 gamma Leu23-Asn254 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL2RG (CD132),uniProtId:P31785-1,ncbiNodeId:9606,antigenRange:23-254,antigenLength:369,antigenImageFileName:MA5-24286_IL2RG_CD132_P31785-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24286_IL2RG_CD132_P31785-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608967

Product Specific Information

In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha, rhIL-2 R beta, rhIL-15 R alpha, recombinant mouse IL-2 R gamma, or recombinant canine IL-2 R alpha is observed. In Western blots, approximately 80% cross-reactivity with recombinant human IL-2 R beta, 50% cross-reactivity with rhIL-15 R alpha and recombinant mouse IL-2 R alpha, and no cross-reactivity with rhIL-2 R alpha is observed.

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.