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Thermo Fisher Scientific MSR1 Monoclonal Antibody (UMAB247), UltraMAB
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Thermo Fisher Scientific

Thermo Fisher Scientific MSR1 Monoclonal Antibody (UMAB247), UltraMAB

상품 한눈에 보기

인간 MSR1 단백질(aa 197-451)을 항원으로 제작된 마우스 모노클론 항체. IHC(P) 및 ChIP 분석에 사용 가능. 비결합형 액상 포맷, 친화 크로마토그래피 정제. -20°C 보관, 동결/해동 반복 피해야 함.

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Thermo Fisher Scientific
카테고리
Monoclonal Antibodies
판매단위
pk

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마지막 업데이트 2025. 08. 04. 오전 11:28
Thermo Fisher Scientific UM800139 MSR1 Monoclonal Antibody (UMAB247), UltraMAB 100 ul pk판매 단위 pk ·
재고 확인 필요
770,300원VAT 포함 847,330원
Thermo Fisher Scientific UM870139 MSR1 Monoclonal Antibody (UMAB247), UltraMAB 30 ul pk판매 단위 pk ·
재고 확인 필요
301,100원VAT 포함 331,210원
재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Thermo Fisher Scientific · Thermo Fisher Scientific MSR1 Monoclonal Antibody (UMAB247), UltraMAB

Applications

Immunohistochemistry (Paraffin) (IHC (P))

  • Tested Dilution: 1:100–1:1200

ChIP assay (ChIP)

  • Tested Dilution: Assay-Dependent

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone UMAB247
Immunogen Human recombinant protein fragment corresponding to amino acids 197–451 of human MSR1 produced in E. coli
Conjugate Unconjugated
Form Liquid
Concentration 0.5–1.0 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions −20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

The CD204 gene encodes class A macrophage scavenger receptors, including three isoforms (types 1, 2, and 3) generated by alternative splicing. These macrophage-specific trimeric membrane glycoproteins are involved in various physiological and pathological processes such as atherosclerosis, Alzheimer’s disease, and host defense.

  • Type 1 and 2 isoforms: Functional receptors mediating endocytosis of modified LDLs.
  • Type 3 isoform: Does not internalize modified LDL due to altered intracellular processing and is retained in the endoplasmic reticulum.
  • Type 3 can inhibit types 1 and 2 when co-expressed, suggesting a regulatory mechanism for scavenger receptor activity.

Diseases associated with MSR1 include Barrett’s Esophagus and Prostate Cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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