
Thermo Fisher Scientific PRDX5 Monoclonal Antibody (OTI4B12), TrueMAB
PRDX5 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC에 적합합니다. 인간, 생쥐, 랫트 반응성을 가지며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로 세포 내 산화 스트레스 관련 단백질 분석에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B12 |
| Immunogen | Full length human recombinant protein of human PRDX5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Peroxiredoxin (Prx) is a peroxidase family involved in cell proliferation, differentiation, and apoptosis. Mammalian Prx proteins (six members) are categorized into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx groups.
- Prx I, II, VI: Cytosolic localization
- Prx III: Mitochondrial localization
- Prx IV: ER and secretion
- Prx V: Found in peroxisome, mitochondria, and cytosol
These proteins exhibit thioredoxin-dependent peroxidase activity using thioredoxin, thioredoxin reductase, and NADPH as reducing systems. Molecular size ranges from 20–30 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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