Thermo Fisher Scientific PIK3C2B Monoclonal Antibody (3E5)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Protein Sequence:
MSSTQDNGEH WKSLESVGIS RKELAMAEAL QMEYDALSRL RHDKEENRAK QNADPSLISW DEPGVDFYSK PAGRRTDLKL LRGLSGSDPT LNYNSLSPQE GPPNHSTSQG

Target Information

Class II PI3 kinases, including PIK3C2B, phosphorylate the 3 position of PI or PI4P.
Although less studied than class I PI3 kinases, class II enzymes are linked to receptor-mediated processes such as insulin signaling, neuronal survival, and growth factor signaling.

Protein kinases transfer phosphate groups from ATP to substrate proteins, mediating signal transduction in eukaryotic cells.
They regulate processes including metabolism, transcription, cell cycle, cytoskeletal rearrangement, apoptosis, and differentiation.
With over 500 gene products, the protein kinase family is one of the largest in eukaryotes and is classified into eight major groups based on catalytic domain sequences.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.