Thermo Fisher Scientific PIM1 Monoclonal Antibody (6A2)
PIM1 단백질을 인식하는 마우스 단클론 항체로, IHC, ICC/IF, ELISA에 사용 가능. 인간 시료에 반응하며, GST 태그가 결합된 재조합 PIM1 단백질로 면역화. 친화 크로마토그래피로 정제된 액상 항체로, -20°C에서 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6A2 |
| Immunogen | PIM1 (AAH20224.1, 1 a.a. ~ 313 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG SVYSGIRVSD NLPVAIKHVE KDRISDWGEL PNGTRVPMEV VLLKKVSSGF SGVIRLLDWF ERPDSFVLIL ERPEPVQDLF DFITERGALQ EELARSFFWQ VLEAVRHCHN CGVLHRDIKD ENILIDLNRG ELKLIDFGSG ALLKDTVYTD FDGTRVYSPP EWIRYHRYHG RSAAVWSLGI LLYDMVCGDI PFEHDEEIIR GQVFFRQRVS SECQHLIRWC LALRPSDRPT FEEIQNHPWM QDVLLPQETA EIHLHSLSPG PSK
Target Information
The proto-oncogene PIM1 is upregulated in prostate cancer. PIM1, a member of the Serine/Threonine protein kinase family, is involved in signal transduction in blood cells. It may influence chromatin structure or silencing by phosphorylating HP1 gamma/CBX3. PIM1 is primarily expressed in hematopoietic and germ line cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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