Thermo Fisher Scientific MYH7 Monoclonal Antibody (MYH7/9183)
Human MYH7 단백질을 인식하는 mouse monoclonal antibody로, IHC(P)에서 1–2 µg/mL 농도로 사용 가능. 단백질 A/G로 정제된 액상 항체이며 PBS + 0.05% BSA buffer에 보관. 심근 및 골격근 연구용으로 적합한 고특이성 항체.
- 카탈로그번호
- 4625-MSM2-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MYH7 Monoclonal Antibody (MYH7/9183)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MYH7/9183 |
| Immunogen | Recombinant fragment (around aa1150–1350) of human MYH7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Skeletal muscle
- Cellular Location: Cytoplasm; myofibril. Thick filaments of the myofibrils.
Target Information
Muscle myosin is a hexameric protein composed of 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits.
This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin, expressed predominantly in normal human ventricle and skeletal muscle rich in slow-twitch type I fibers.
Altered expression correlates with cardiac contractile velocity and changes during thyroid hormone depletion or hemodynamic stress.
Mutations in MYH7 are linked to familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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