Thermo Fisher Scientific MYH7 Monoclonal Antibody (MYH7/727)
Human MYH7 단백질을 인식하는 mouse monoclonal antibody로, IHC(P)에서 1–2 µg/mL로 사용 가능. Skeletal muscle을 양성 대조로 사용. 단백질 A/G 정제, 4°C 보관. 심근 및 골격근 연구용에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MYH7/727 |
| Immunogen | Recombinant full-length human MYH7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Skeletal muscle
- Cellular Location: Cytoplasm; myofibril. Thick filaments of the myofibrils.
Target Information
Muscle myosin is a hexameric protein composed of two heavy chain subunits, two alkali light chain subunits, and two regulatory light chain subunits.
This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin, expressed predominantly in normal human ventricles and in skeletal muscles rich in slow-twitch type I fibers.
Changes in the ratio of beta and alpha heavy chain subunits correlate with cardiac muscle contractile velocity.
Expression is affected by thyroid hormone levels and hemodynamic load.
Mutations in MYH7 are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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