Thermo Fisher Scientific FGFR4 Recombinant Superclonal Antibody (14HCLC)
FGFR4 단백질을 인식하는 토끼 유래 Recombinant Superclonal 항체로, WB 및 ICC/IF에 적합합니다. 단클론의 특이성과 폴리클론의 감도를 결합해 일관된 결과를 제공합니다. 인간 FGFR4(aa 22-141)에 대응하며, Protein A로 정제된 액상 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–3 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–3 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 14HCLC |
| Immunogen | Recombinant protein corresponding to amino acids 22–141 of human fibroblast growth factor receptor 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532627 |
Product Specific Information
Recombinant rabbit Superclonal™ antibodies are composed of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
Each lot contains a defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability.
This product was formerly known as “Recombinant Polyclonal Antibody” and is now branded as “Recombinant Superclonal™ Antibody” with unchanged performance.
Target Information
FGFR4 (Fibroblast Growth Factor Receptor 4) belongs to the FGFR family of receptor tyrosine kinases that regulate angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair.
FGFR4 is required for normal down-regulation of CYP7A1 expression in response to FGF19 and plays roles in postnatal lung development and skeletal muscle lineage formation.
Dysregulation of FGFR4 has been implicated in cancer, rheumatoid arthritis, and diabetic retinopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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