Thermo Fisher Scientific TRPA1 Polyclonal Antibody, HRP
TRPA1 단백질을 인식하는 HRP 결합 폴리클로날 항체로, Western blot, IHC, ELISA 등에 사용 가능. 사람, 마우스, 랫, 기니피그, 제브라피시에 반응. 항원 친화 크로마토그래피로 정제되었으며, 4°C 암소 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:250 |
| Immunohistochemistry (Frozen) (IHC (F)) | 0.5–1.0 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Guinea pig, Human, Mouse, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide made to a region within the N-terminus (residues 1–100) of the human TRPA1 protein |
| Conjugate | HRP |
| Form | Liquid |
| Concentration | 0.84 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_11152996 |
Product Specific Information
- The target sequence has 69% sequence homology with rat.
- Suggested positive control: human brain membrane fraction.
Target Information
TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction.
TRPA1 is a transformation-associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons.
Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage.
It is also expressed outside of the CNS and is dysregulated during oncogenic transformation.
The structure of TRPA1 is related to ankyrin and transmembrane proteins.
Although its specific function is not fully determined, studies suggest it plays a role in signal transduction and growth control.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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