Thermo Fisher Scientific MMP3 Monoclonal Antibody (OTI2E7), TrueMAB
인간 MMP3 단백질(aa 246-477)에 특이적인 Mouse IgG2b 모노클로날 항체로, Western blot에 최적화됨. Lyophilized 형식으로 제공되며, PBS/trehalose 버퍼에 보관. 연구용으로 세포 외 단백질 분해 및 조직 재형성 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E7 |
| Immunogen | Human recombinant protein fragment (aa 246–477 of human MMP3, produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MMP3 (stromelysin-1) is a member of the peptidase M10A subfamily. It is secreted as a pro-protein and activated by extracellular cleavage.
MMP3 binds zinc and calcium ions and exhibits metallo-endopeptidase activity, degrading collagen, gelatin, fibronectin, and laminin.
It plays a key role in wound repair and tissue remodeling. Mutations in MMP3 can be associated with coronary heart disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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