Thermo Fisher Scientific HTR2B Polyclonal Antibody
HTR2B 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 시료에 반응하며 IHC(P) 실험에 최적화. 항원 친화 크로마토그래피로 정제된 액상 항체로, 장기 보관 시 -20°C에서 안정적 유지.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human 5HT2B Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550689 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Orangutan, Monkey (100%)
Marmoset, Bat (95%)
Horse (90%)
Target Information
HTR2B is a G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances.
Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors.
HTR2B also plays a role in perception of pain and regulation of behavior.
It is required for normal proliferation of embryonic cardiac myocytes and normal heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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