Thermo Fisher Scientific HTR2B Polyclonal Antibody
HTR2B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot과 IHC(Paraffin)에 사용 가능. 인간 및 영장류에서 높은 종간 일치율을 보이며, 액상 형태로 제공. 연구용으로 세로토닌 수용체 기능 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human 5HT2B Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.71 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550688 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%)
Bovine, Rabbit, Pig (88%)
Target Information
HTR2B is a G-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformational change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR2B also plays a role in pain perception and behavior regulation. It is required for normal proliferation of embryonic cardiac myocytes and normal heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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