Thermo Fisher Scientific SARS-CoV/SARS-CoV-2 NP Recombinant Human Monoclonal Antibody (CR3018 (03-018))
SARS-CoV 및 SARS-CoV-2 N 단백질을 인식하는 인간 유래 재조합 단클론 항체. ELISA 및 ICC/IF에 사용 가능. 높은 특이성과 재현성 제공. 단백질 A로 정제된 액상 항체로, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CR3018 (03-018) |
| Immunogen | The original antibody was generated by cloning the variable regions of the scFvs selected from phage display libraries into separate vectors for IgG1 heavy-chain and light-chain expression. The harvested supernatants were then purified on protein A columns. The original immunogen was the whole irradiated virion. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074766 |
Product Specific Information
Specificity: This antibody binds the amino acid residues between 11–19 of the N protein of the SARS-CoV as well as SARS-CoV-2 (COVID-19) nucleocapsid protein.
Target Information
Human coronaviruses are major causes of upper respiratory tract illnesses such as the common cold. Coronaviruses are positive-stranded RNA viruses with large genomes (27–31 kb).
The first step in coronavirus infection is binding of the viral spike protein (139 kDa) to host cell receptors. The spike protein is the main surface antigen of the coronavirus.
The most prominent protein in SARS virus-infected culture supernatants is a 46 kDa nucleocapsid protein, suggesting its strong immunogenicity and potential diagnostic value.
SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid and is the most abundant viral protein, making it a useful target for research and diagnostic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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