Thermo Fisher Scientific BHLHE40 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000-1:15,000

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-Dependent

-

Immunocytochemistry (ICC/IF)

1:500-1:1,000

-

Flow Cytometry (Flow)

2-5 µg/mL

View 1 publication 1 publication

ELISA (ELISA)

Assay-Dependent

-

Immunoprecipitation (IP)

Assay-Dependent

-

ChIP assay (ChIP)

Assay-Dependent

-

ChIP-sequencing (ChIP-Seq)

Assay-Dependent

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Residues between 350 and the C-terminus (412) of human DEC1 using the numbering given in entry NP_003661.1 (GeneID 8553) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BHLHE40,uniProtId:O14503-1,ncbiNodeId:9606,antigenRange:350-412,antigenLength:412,antigenImageFileName:PA1-16546_BHLHE40_O14503-1_Rabbit.svg,antigenImageFileNamePDP:PA1-16546_BHLHE40_O14503-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2065348

Product Specific Information

Suggested positive control: antigen standard for BHLHB2 (transient overexpression lysate).

Target Information

Differentiated embryo-chondrocyte expressed gene 1 (DEC1) is an important protein involved in embryonic cell differentiation, proliferation, and apoptosis. It has also recently been shown to be regulated by hypoxia. The loss of DEC1 expression may be an early event in the development of lung cancer, while DEC1 may be up-regulated by hypoxia in other cancers and in more extreme hypoxia it may have a role in cell death.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.